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NNMT is over-expressed in a large proportion in renal cell cancers

GLP-1 agonists and metabolic receptors Semaglutide and tirzepatide both act on GLP-1 receptors, though tirzepatide also activates GIP receptors

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In animal studies, AOD-9604 has been found to reduce body weight without significantly affecting blood sugar levels, which is a common side effect of other weight loss drugs