[DOI] [PMC free article] [PubMed] [Google Scholar] 188
Taixiang W, Munro AJ, Guanjian L
Among these members, ASCT2 (alanine-serine-cysteine transporter 2) is considered to be the most important glutamine transporter in tumor cells, which is encoded by the SLC1A5 gene, is a Na + dependent neutral amino acid transporter (Scalise et al., 2018
In HCC, ERS is implicated in tumor cell proliferation, migration, invasion, angiogenesis, and resistance to chemotherapy
H.Pigment epithelium-derived factor (PEDF) plays anti-inflammatory roles in the pathogenesis of dry eye disease
The pathology proceeds through different stages: from simple hepatic steatosis, it progresses toward non-alcoholic steatohepatitis (NASH), fibrosis, cirrhosis and in the most severe cases, toward hepatocellular carcinoma (HCC) [79]