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The compounds direct activity at GHS-R1a receptors expressed on cardiomyocytes produces a transient inotropic effect an increase in the force of cardiac contraction within 15 minutes of administration

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doi: 10.1006/bbrc.1995.1083

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By upregulating genes related to lipid peroxidation and iron absorption, p53 can cause ferroptosis

The CD38/NAD/SIRTUIN1/EZH2 axis mitigates cytotoxic CD8 T cell function and identifies patients with SLE prone to infections