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In proximal renal tubular epithelial cells (TECs), autophagy inhibition, such as chloroquine or ATG7 depletion, reduces fibrosis, suggesting that autophagy may promote injury (Nam et al., 2019)

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In addition, BACH1 is also polyubiquitinated by Fbox and leucinerich repeat protein 17 (FBXL17) [ 33 , 34 ] and hemeoxidized IRP2 ubiquitin ligase 1 (HOIL1)

Significantly more accessible than IV

N-acetyl-L-cysteine protects against cadmium-induced neuronal apoptosis by inhibiting ROS-dependent activation of Akt/mTOR pathway in mouse brain

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