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Furthermore, the CoFe2O4 nanoplatform (CFAP), functionalized with polyethylene glycol (PEG)-coated gold nanoparticles, effectively depletes GSH, disrupts intracellular redox balance, and induces immunogenic cell death, exhibiting promising clinical potential for solid tumor treatment (Zeng et al., 2024)
Although these direct antioxidant effects are observable in vitro, their significance in vivo appears limited, stemming from low plasma concentrations of NAC and the prevalence of more abundant endogenous antioxidants such as GSH, ascorbate, and antioxidant enzymes (e.g., SODs, GPs, CAT) [6,38,39]
doi: 10.1111/nmo.13682 103
Acta Physiol Plant 38(9):110
C Aged rats of mixed sex and age (22-26 months) were randomly assigned to a control/untreated group or a Dihexa treated group (2 mg/kg/day)
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