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As for the catabolism of ornithine, the resulting 1 -pyrroline-5-carboxylate is converted to glutamate via the action of ALDH4A1

10.1017/wsc.2019.71 129 MatharageH.JayaweeraM.BandaraN.GunawardanaB

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[PubMed] [Google Scholar] 13.Kuchta K., Schmidt M., Nahrstedt A

This pharmacokinetic profile, combined with its amphiphilic character (allowing it to cross the blood-brain barrier), has sustained interest in DSIP as both a research tool and a subject of investigation in its own right