Reviews describe regenerative and protective actions, roles in skin regeneration, and modulation of multiple cellular pathways but this is largely mechanistic and preclinical work, not large human efficacy trials
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However, its incidence has gradually increased and is expected to reach the levels observed in Western countries
In our opinion, this is mainly due to the fact that many laboratory-stage techniques are limited by safety and ethical concerns
Furthermore, we found that LA could elevate the level of GSH, which was consistent with the research that macrophage migration inhibitory factor (MIF) increased intracellular GSH content which protected against oxidative damage of tubular epithelial cell in vivo and in vitro (Unruh et al., 2019)