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For example, short-chain fatty acids (SCFAs) enhance the production of bactericidal reactive oxygen species (ROS) by macrophages through histone deacetylase (HDAC) inhibition (65)

Thompson P, Ferrajoli A, Keating M, Banerjee P, Andreeff M , Rezvani K, Wierdaiw W

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Regarding skin pigmentation, GSH inhibits tyrosinase, the key enzyme responsible for melanin synthesis, thereby shifting melanogenesis away from the production of darker eumelanin and toward the formation of lighter pheomelanin

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Effect of biomechanical stress on endogenous antioxidant networks in bovine articular cartilage