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BBB blood-brain-barrier HGF hepatocyte growth factor neurotrophic factors are large proteins that lack significant BBB penetrability

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For example, oral administration of taurine may promote the exercise performance initially, but long-term exercise using taurine does not have a significant effect, suggesting that oral intake of taurine at the initial level may promote the exercise performance, but longer duration of exercise may not retain the cellular taurine levels (Rahman et al., 2011

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Cagrilintide Moreover, cagrilintide is a long-acting amylin analog developed by Novo Nordisk