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These findings have generated substantial interest in senolytic approaches to age-related disease research

EMD 1214063 and EMD 1204831 constitute a new class of potent and highly selective c-Met inhibitors

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The dopamine receptor DRD2 has been identified as a novel therapeutic target to remodel the immunosuppressive tumour microenvironment by promoting M1 macrophage polarisation, inhibiting the NF-B signalling pathway, and inducing pyroptosis in breast cancer cells [62], which provides a promising new treatment direction for breast cancer

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While no officially approved human dosing exists, community experience and extrapolation from animal research provide useful guidance