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Essentials of medical pharmacology

Brown NC, Andreazza AC, Young LT

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Nusinersen, an anitisense oligonucleotide, has been recently approved by the US FDA for treatment of SMA ( Huntington Disease Huntington disease (HD) is a rare genetic autosomal dominant neurodegenerative syndrome triggered by expanded CAG repeats in the huntingtin gene, which leads to pathological elongation of huntingtin with a polyglutamine tract

They concluded that There is little convincing evidence in favor of glutathione as a therapy for hyperpigmentation at the present time and that More evidence in the form of high quality trials with better study design, larger sample size, and long-term follow-up is vital