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FEBS Open Bio 5 , 492501 (2015)

Some medications that may interfere include metformin, PPIs, chloramphenicol, some antibiotics, and anticonvulsants

Pregnant and breastfeeding women should avoid glutathione due to limited safety data

The nanoparticles of silibinin exhibited antioxidant effects against intracellular oxidative stress by upregulating the Nrf2/ARE pathway, reducing ROS, modulating antioxidant enzyme responsiveness, and inhibiting downstream pathways of mitochondrial damage (Ding et al., 2022)

Food and Drug Administration and other relevant authorities before considering use

[ 13 C 2 , 15 N]-GSH-NEM (m/z 436 307 m/z