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these micronutrients are utilized as cofactors, substrates, or components of enzymes in glycolysis and the citric acid cycle (6, 7)

Grids were blotted using Vitrobot Mark IV (Thermo Fisher Scientific) with a blot force of -1, blot time of 1 s, at 100% humidity and 8 C, and plunge-frozen in liquid ethane cooled by liquid nitrogen

Bcl-2 expression causes redistribution of glutathione to the nucleus

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Next, 6 10 6 cells (1 OD 600 (optical density at 600 nm) = 1 10 7 cells) were transferred into PBS with 0.1% BSA (PBS-B), containing 50100 M BP

Indeed the activation of prodrugs in GST overexpressing cells may lead to high concentrations of an active drug, as compared to normal cells with moderate enzyme levels