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Also searched were the Agency for Healthcare Research and Quality evidence reports, Clinical Evidence, the Cochrane database, Essential Evidence, the Institute for Clinical Systems Improvement, the National Guideline Clearinghouse database, and the U.S

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A randomised controlled trial following 131 postmenopausal women found that 5 grams of specific collagen peptides daily over 12 months produced a 4.2 per cent increase in bone mineral density at the lumbar spine and a 7.7 per cent increase at the femoral neck