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Full safety profile Multiple species 96-well Service outputs aProximate TM Evaluation of KIM-1, NGAL, and clusterin, three FDA-approved biomarkers of kidney toxicity Cell viability: ATP, LDH, and TEER measurements Assays Kidney toxicity assays Assessment of renal drug safety Models aProximate TM kidney proximal tubule cells (from human, mouse, rat, and dog) Timeline 2-3 months How can Newcells kidney tissue models be used to assess renal toxicity

Endurance athletes may be especially vulnerable because they may attempt to replace sweat losses by drinking large volumes of low electrolyte alkaline water instead of isotonic fluids formulated for proper rehydration (83)

Areas with denser blood vessels have higher biochemical transport efficiency of free fatty acids into lymphatic vessels

NAC is a free radical scavenger and thus supports epithelial cell health and healthy cilia activity in the respiratory tract