Convenience : After fixing the deficiency, maintenance injections can be done monthly
In the duodenum, pancreatic enzymes cleave B12 from R-proteins, allowing binding to intrinsic factor produced by gastric parietal cells
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Vitamin B12 deficiency has occurred in breastfed infants of vegetarian mothers whose diets contain no animal products (e.g., eggs, dairy), even though the mothers had no symptoms of deficiency at the time