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Liu et al (2017) reported that NF-B responds to cytokine IL-1, and its activation induces the expression of inflammatory cytokines, chemokines, and adhesion molecules

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In a randomized controlled trial, the topical steroid combination (betamethasone) with a narrow-band UVB (NB-UVB) and topical calcipotriol therapy substantially improved repigmentation at six months compared to NB-UVB alone and NB-UVB with topical calcipotriol 25

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Severe psoriasis added 6.2% absolute risk of major adverse cardiac events.[55] Gelfand et al used the General Practice Research Database (GPRD) to determine if psoriasis is an independent risk factor for myocardial infarction