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Research in Pharmaceuticals (MDPI, 2025) reviews BPC-157's mechanisms across tissue injury and repair models, documenting its effects via VEGFR2-Akt-eNOS angiogenic pathways, nitric oxide signaling, and growth hormone receptor expression upregulation in tendon fibroblasts

Meanwhile, it increased the levels of TNF- and IL-1 and decreased the level of IL-10 (Figure 6G)

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Adhikari M, Negi B, Kaushik N, Adhikari A, Al-Khedhairy AA, Kaushik NK, et al