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Description

Siracusano M, Riccioni A, Abate R, Benvenuto A, Curatolo P, Mazzone L

2023;67 [Google Scholar] Aminoacyl-tRNA synthetases

Jason et al., 2009)

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Unlike the MTHFD1 encoded enzyme that is a tri-functional enzyme harboring N 5 , N 10 -methenyl-THF (5,10-methenyl-THF) cyclohydrolase, 5,10-methylene-THF dehydrogenase, and 10-formyl-THF synthetase activities, the MTHFD1L encoded enzyme only possesses 10-formyl-THF synthetase activity