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In clinical setting, high IFN- expression is associated with improved outcomes in the response to immune checkpoint blockade [44, 45]

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The 2mg/mL concentration (5mL bacteriostatic water) provides the best balance of concentration, stability, and dosing precision

GI symptom rates at the 12 mg dose included nausea (38-43%), diarrhea (33-35%), constipation (21-25%), and vomiting (20-21%)

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