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This means it has antimetastatic effect as was showed in the research of spontaneous tumorigenesis in female mice mostly with tumors of the reproductive organs as mammary glands and ovaries

BDNF is a neurotrophic factor that promotes the growth and survival of neurons, enhancing synaptic plasticity and improving overall brain function

Serum BDNF discriminates Parkinsons disease patients with depression from without depression and reflect motor severity and gender differences

In vivo studies demonstrated that diabetic mice exhibit markedly lower hepatic LONP1 protein levels compared with lean mice, suggesting that LONP1 downregulation may contribute to the development of insulin resistance and type 2 diabetes [118, 119] (Fig

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