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But no substantial studies have shown a direct effect of vitamin B12 on human weight loss efforts
In addition, most B12 supplements come in the form of pills, and most people do not receive the full benefit from digesting a pill while some cannot absorb the nutrients at all
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In mouse models of highfat dietinduced liver steatosis, it significantly inhibits hepatic NNMT activity, reduces NAM methylation, increases NAD+ and SAM levels, enhances mitochondrial fatty acid oxidation, reduces hepatic triglyceride and lipid accumulation, lowers lipotoxicity markers (e.g., malondialdehyde, transaminases), improves hepatocellular injury, and reverses steatosis