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Lipogenesis Inhibition In adipocyte models, 5-Amino-1MQ suppresses lipogenesis (EC50 = 30 M in 3T3-L1 adipocytes) while increasing intracellular NAD+ concentrations

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The resulting anemia is known as megaloblastic anemia and is the symptom for which the disease, pernicious anemia, was named (3)

Reducing dead space ensures the patient gets a full dose without wastage

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