For example, magainin 2 was found to have selective cytotoxicity to tumor cells, which can kill a variety of tumor cells at a peptide concentration of 510 times lower than the peptide concentration required to kill normal cells
Jinibixxi d-degradazzjoni tal-kollaen permezz ta' mekkanimi ta' mira doppja-: Inibixxi l-espressjoni tal-MMP: Jirregola l-espressjoni tal-eni MMP-1 (collagenase) u MMP-3 (matrilysin), u jnaqqas id-degradazzjoni enimatika tal-fibri tal-kollaen
PMID: 10707891
A nasal spray must penetrate nasal mucosa, possibly deal with mucociliary clearance, and may have somewhat reduced bioavailability
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The statistics paint a grim picture: non-small cell lung cancer, the most common histological subtype, claims more lives than breast, prostate, and colon cancers combined, largely because the majority of patients are diagnosed at advanced stages where curative surgery is impossible and systemic chemotherapy becomes the mainstay
