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NAD+ plays a key role by activating sirtuins (SIRT1 and SIRT6) that help maintain these proteins [19]

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(PubMed) Agnew-Blais JC, Wassertheil-Smoller S, Kang JH, et al

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Am J Epidemiol 187(1):7581 Nagata C et al (2015) Associations of acrylamide intake with circulating levels of sex hormones and prolactin in premenopausal Japanese women