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Early evidence for the potential efficacy of this route was published in 1999, where 18 patients with B12 deficiency treated exclusively with 712 days of 2 mg of sublingual cobalamin daily had 4 times higher B12 levels compared to pre-treatment, reaching therapeutic ranges ( There have also been further studies comparing treatment outcomes from the sublingual route to the more established IM and oral routes
This isn't just a supplement
Buying multiple vials when sales occur can significantly reduce overall costs
Jaffar HM, Al-Asmari F, Khan FA, Rahim MA, Zongo E
However, emerging KD modifications, such as the MAD or MCT-KD, have shown improved tolerability in some studies [199, 200], suggesting their potential for better long-term adherence
Providing supplemental cysteine and glycine in the diet could be a safe, inexpensive, and innovative approach to increase GSH synthesis and concentrations and thus combat oxidative stress and prevent chronic complications in patients with diabetes
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