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In two field studies, the plasma and erythrocyte ChE activities were measured in adults and young children

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Amitriptyline enhances central pain modulation through inhibition of norepinephrine and serotonin reuptake

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However, limitations exist in the form of in vivo instability, the reliance on carriers that are biocompatible and robust and limited sites of application (local and direct) (Park et al

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