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In skin, GHK-Cu signals fibroblasts to produce collagen, modulates matrix metalloproteinases for balanced tissue remodeling, and triggers expression changes in approximately 31 percent of human genes toward a younger profile 1 9

doi: 10.1007/s00280-020-04135-8 34 LiuYZhuGHanLLiuJMaTYuH

[DOI] [PMC free article] [PubMed] [Google Scholar] 177.Wang X, Seo YA, Park SK

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This oxidative stress is particularly damaging because of METHs effects on dopamine, which undergoes autoxidation, leading to the generation of dopamine quinones and ROS (Figure 1)

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