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Hexokinase-2, a glycolytic enzyme, contributes to intestinal homeostasis, and its deletion has been associated with diminished cell death and inflammatory bowel disorders 20

Consequently, the recovery of the severe muscle weakness and severe heart disturbances might be promptly associated [80]

33 : 58055812 Nakamura J, Koh N, Sakakibara F, Hamada Y, Hara T, Sasaki H et al

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Mechanistic study has shown that PGC-1 plays an important role in the modulation of the UPR through coactivating ATF6, a well-characterized sensor in UPR, thus contributing to skeletal muscle adapt to exercise training