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Supernatant was discarded, and cells were subsequently incubated in 0.5 mL KRBH containing 0.1% BSA,1 mM glucose, and 10 M adrenaline (MCE, HY-B0447B) at 37 C for 1 h

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Although the applicant provided studies demonstrating that XENOVIEW [TM] can detect gas diffusion abnormalities in patients that traditional imaging such as CT cannot, or can detect these abnormalities earlier than currently available methods, these studies do not appear to demonstrate that subsequently, treatment planning or disease management was affected

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