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Medication: Certain medications, such as antihistamines and decongestants, can also trigger IC symptoms

doi: 10.1128/mBio.02094-21 53 DavisD

Among them, UQCRB is one of the subunits of the mitochondrial respiratory chain complex III, and mutations in UQCRB increase mtROS production and activate HIF-1 transactivation, promoting vascular neovascularization, a process that can be regulated by UQCRB inhibitors (209)

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