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137 Similar positive results have been observed in several other studies

First-line encorafenib plus binimetinib and pembrolizumab for advanced BRAF V600-mutant melanoma: Safety lead-in results from the randomized phase III STARBOARD study

The hydrogen peroxide, although its not a specie very reactive, it is na agent able to inactivate enzymes, mainly by oxidation of essential thiol groups

For the IFN-I bioassay, 5 10 4 3T3 cells containing an interferon-sensitive response element (ISRE) fused to luciferase 51 were plated per well into 96-well white-bottom plates (Greneir 655083) in DMEM containing 10% FBS, 100 U/ml penicillin and 100 g/ml streptomycin

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