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El nivel intracelular de glutatin en humanos suele ser de alrededor de 1-2 mM, varios cientos de veces mayor que el nivel observado en el plasma sanguneo, que es de aproximadamente 2 M en condiciones normales

The activity and expression of NRF2 were decreased in many AKI and CKD animal models, suggesting that NRF2 was an important mediator in the pathogenesis and progression of AKI and CKD [204, 205]

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The AWARD- 6 trial revealed that dulaglutide was not inferior to liraglutide in terms of lowering HbA1c