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Familial forms of this disorder have been identified linking the gene that encodes -synuclein, SNCA, as well as a number of other genes to PD pathogenesis (reviewed in (Lesage and Brice 2009

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Additionally, PGM, another p53 target gene, amplifies EMP activity under p53 loss, thereby promoting the EMP

(PubMed) Berr C, Balansard B, Arnaud J, Roussel AM, Alperovitch A

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