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Higher proteotoxic stress rather than mitochondrial damage is involved in higher neurotoxicity of bortezomib compared to carfilzomib
J Biol Chem 270, 443850
Sep 2008;38(5):1081-106, vii
With respect to the comparison between cortisone and stem cells compared to BPC-157: Cortisone and stem cells are not considered performance enhancing drugs and are not banned substances by the WADA
Type 2 diabetes: Oxidative stress plays a role in diabetes, and people with type 2 diabetes have lower glutathione levels on average.[ref] Pancreatitis: Chronic pancreatitis causes oxidative stress
These metabolic-derived DAMPs, together with potential pathogen-associated molecular patterns (PAMPs) in PCC, may synergistically enhance immune cell activation, forming a critical link between mitochondrial metabolic dysfunction and the subsequent inflammatory response
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