For example, chitosan-based PcDNA3.1-dsNKG2D-IL-21 plasmid nanoparticles were prepared by linking a two-gene fragment encoding NKG2D and the extracellular domain of interleukin (IL)-21 gene and inserting into the pcDNA3.1 plasmid, which can delay tumor growth by activating NK cells in vivo after tumor tissue accumulation (87)
Clinical Safety and Efficacy of Nilotinib or Dasatinib in Patients With Newly Diagnosed Chronic-Phase Chronic Myelogenous Leukemia and Pre-Existing Liver and/or Renal Dysfunction
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The study concluded that IFN- might serve as a prognostic marker for HPV clearance, suggesting that its presence is a favorable indicator for the natural regression of HPV-related lesions
Matsuoka K, Nishiumi S, Yoshida M, Kodama Y
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