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It is a substrate for -ketoglutarate dehydrogenase (OGDH) in oxidative reactions generating succinyl-CoA and isocitrate dehydrogenase 1 (IDH1) or isocitrate dehydrogenase 2 (IDH2), which catalyze the reductive carboxylation reaction converting -KG to isocitrate

Without enough, the immune system can swing between being sluggish (letting infections drag on) and being overactive (triggering unnecessary inflammation or food sensitivities)

Early endoscope-assisted hematoma evacuation in patients with supratentorial intracerebral hemorrhage: case selection, surgical technique, and long-term results

Whang YM, Jung SP, Kim M-K, Chang IH, Park SI

Philippines FDA Registration Number: To be updated