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The triple agonist mechanism appears to match or slightly exceed tirzepatide for blood sugar management , likely because the glucagon component, while it can raise blood sugar in isolation, works synergistically with GLP-1 and GIP activation to produce a net positive effect on glucose regulation

TGR, thioredoxin-glutathione reductase

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Older patients or those with multiple comorbidities may experience slower improvement

E N D Presentation Transcript COLLEGE OF PUBLIC HEALTH AND HUMAN SCIENCES The Effects of Glutathione-S-Tranferase Polymorphisms on Sulforaphane Metabolism Jeannie Allen1,2,3, Anna Hsu1,4, PhD