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Similarly, hypoxia-inducible factor 1-alpha (HIF-1) upregulates the miR-23a/24 cluster, driving a metabolic shift toward glycolysis under hypoxic conditions and thereby accelerating cancer progression [112]

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There is an important nomenclature nuance here that researchers should be aware of

530532 Canonical MarRs that repress the expression of drug efflux pumps may bind antibiotics or other small organic molecules leading to the transcriptional depression of the genes associated with an adaptive response to antibiotic stress, e.g., efflux systems