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It may help restore the muscle architecture and vascular density needed to handle normal exertion though patients with PEM should approach any intervention with careful pacing and clinical oversight

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The absence of longitudinal clinical data in FAERS precludes adjustment for these factors

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Epitalon has been shown to increase IL-2 mRNA expression in both human in vitro and animal in vivo studies, but its effects appear especially pronounced in aged tissues [4, 48], pointing toward a role in immunorejuvenation rather than broad immunostimulation