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The PTT-ferroptosis combination shows considerable anti-tumor potential

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Similarly, the drugs of the fibrates (212, 213) upregulate the expression of HO-1 mRNA and protein to increase bilirubin levels

However, about 10-15% of acetaminophen is metabolized by CYP2E1 into a toxic metabolite known as NAPQI (N-acetyl-p-benzoquinone imine).[ref] Detoxification with glutathione: NAPQI then needs to be neutralized with glutathione, which is catalyzed using the GST genes

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Small amounts of CH 4 were also observed (0.05 mol gcat 1 h 1 ), but CO was clearly the dominant product