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Why All Peptides Might Not Be as Safe as They Sound TO DATE, THE FDA has approved more than 100 peptides for use as drugs

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Deamidation Deamidation occurs when asparagine (Asn) or glutamine (Gln) residues in the peptide chain lose their amide group and convert to aspartic acid or glutamic acid respectively

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In vitro experiments demonstrated that cancer-associated adipocytes upregulate the hexosamine biosynthetic pathway (HBP), leading to O-GlcNAcylation and stabilization of the YAP protein