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It is a multi-system breakdownand multi-system breakdowns are exactly what root-cause medicine is designed to address

Intensive Care Med

Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract. Current Pharmaceutical Design

A cold compress can help reduce inflammation and swelling, while a hot compress can help improve blood flow and promote healing

This response was more limited to the gut, so may have helped more in people with gastrointestinal issues like irritable bowel syndrome and Crohns

In general, avoid skipping doses, as blood levels will drop, and the medication will not work effectively.