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3.1 A schematic diagram showing the enteral routes of drug administration (oral, sublingual and rectal) and their relative susceptibility to first-pass elimination, influencing the absorption and bioavailability of a drug

It's not the B12 causing the gain, but the lack of B12 impairing your body's ability to maintain its usual energy output

Bioavailability often approaches 100 percent for subcutaneous delivery, which is why injections remain the gold standard for peptide administration

Cancer Res 56(5):11111117 Dirkx AE et al (2003) Tumor angiogenesis modulates leukocyte-vessel wall interactions in vivo by reducing endothelial adhesion molecule expression

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therefore, this should be a period of heightened surveillance