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Research also examines BPC-157 effects on medial collateral ligament healing in animal models, with studies investigating both local and systemic administration routes

Prados MD, Schold SC Jr, Fine HA, Jaeckle K, Hochberg F, Mechtler L, Fetell MR, Phuphanich S, Feun L, Janus TJ, et al

doi: 10.1074/jbc.RA119.008180 21 WickerCAHuntBGKrishnanSAzizKParajuliSPalackdharrySet al

doi: 10.1177/0961203311413412 94 ZhanYGuoYLuQ

Overexpression of Nos2 promotes the secretion of tumor necrosis factor (TNF) and interleukin1 (IL1) and subsequently induces a secondary inflammatory reaction and the generation of oxygen free radicals (Foncea, Carvajal, Almarza, & Leighton, 2000