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Synthesis of NADPH B

Reduced ventilation due to loss of elastic recoil in the emphysematous lung, together with the loss of the capillary bed and the generalized inhomogeneity of ventilation due to the patchy nature of these changes, leads to areas of V A /Q mismatching that result in arterial hypoxemia

International Journal of Molecular Sciences , 23 (12), 6395 Adam, I., Dewi, D

Activated caspase-8/10 induces apoptosis through two parallel pathways (Legembre et al., 2002): it either directly cleaves and activates caspase-3 or cleaves the pro-apoptotic Bcl-2 family protein Bid to generate truncated Bid (tBid)