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Because of the potential risks of high-dose magnesium supplementation, especially in those with impaired kidney function, supplementation with magnesium should be conducted under medical supervision

doi: 10.1038/sj.mp.4001888 314 MockingRJAssiesJLokARuheHGKoeterMWVisserIet al

& Sessa W.C

While the heart-specific targets of MOTS-c are still being investigated, these findings open the door to the peptides potential use in supporting cardiovascular health

Including iron-rich foods (red meat, beans, fortified cereals) and folate sources (green vegetables, pulses, fortified bread) can support red blood cell production

A 2026 meta-analysis of over 1,300 people found the strongest anti-aging benefit from peptides actually came from oral supplements, not the serums most people are applying to their face