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Collectively, the neuro-inflammatory response is emerging as a pivotal element in the pathophysiology of migraine, characterized by intricate interactions within the neuro-glio-vascular network

Carbohydrate intake elevates blood glucose and insulin, both of which stimulate somatostatin release from pancreatic delta cells

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10.1007/s40262-017-0546-0

Membrane-bound phosphoinositide 3-kinase (PI3K) is the most common mediator of mTOR activation, forming the core of the PI3K/AKT/mTOR pathway along with AKT (45)

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