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doi: 10.1016/s1097-2765(00)80425-6 15 PhilpottCCJadhavS

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Engeletin, a flavonoid from Smilax glabra , suppressed Toll-like receptor 4-NF-B signaling, reduced the expression of IL-1, IL-6, and TNF-, and inhibited macrophage polarization from the pro-inflammatory M1 phenotype

These approaches have demonstrated potential in lowering inflammation levels and enhancing overall brain health [44]

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