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GSH synthesis declines with age (just as we need it most) and GSH stores can be quickly depleted by trauma from illness or injury

The convergence of gonadotropin response and these pathway on steroidogenesis in female and male reproductive tissues is discussed below

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Omega-3 PUFAs derived from food consumption, undergo partial metabolism by anaerobic bacteria like Bifidobacteria and Lactobacilli in the distal intestine, consequently affecting the composition of the gut microbiota (98)